Minicircle and Miniplasmid DNA Vectors : (Record no. 12556)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 06254cam a2200829Ia 4500 |
| 001 - CONTROL NUMBER | |
| control field | ocn828933132 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OCoLC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20171224114221.0 |
| 006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS--GENERAL INFORMATION | |
| fixed length control field | m o d |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr cnu|||unuuu |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 130305s2013 gw ob 001 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | N$T |
| Language of cataloging | eng |
| Description conventions | pn |
| Transcribing agency | N$T |
| Modifying agency | E7B |
| -- | DG1 |
| -- | CUS |
| -- | NOC |
| -- | OCLCO |
| -- | YDXCP |
| -- | OCLCA |
| -- | NLGGC |
| -- | OCLCF |
| -- | EBLCP |
| -- | UKMGB |
| -- | IDEBK |
| -- | DEBBG |
| -- | OCLCQ |
| -- | COO |
| -- | NKT |
| 016 7# - NATIONAL BIBLIOGRAPHIC AGENCY CONTROL NUMBER | |
| Record control number | 016300416 |
| Source | Uk |
| 019 ## - | |
| -- | 829460534 |
| -- | 961671411 |
| -- | 962584608 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9783527670420 |
| Qualifying information | (electronic bk.) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 3527670424 |
| Qualifying information | (electronic bk.) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9783527670437 |
| Qualifying information | (electronic bk.) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 3527670432 |
| Qualifying information | (electronic bk.) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| Cancelled/invalid ISBN | 9783527324569 |
| 029 1# - (OCLC) | |
| OCLC library identifier | AU@ |
| System control number | 000051628906 |
| 029 1# - (OCLC) | |
| OCLC library identifier | AU@ |
| System control number | 000053032883 |
| 029 1# - (OCLC) | |
| OCLC library identifier | CHBIS |
| System control number | 010026927 |
| 029 1# - (OCLC) | |
| OCLC library identifier | CHVBK |
| System control number | 306231786 |
| 029 1# - (OCLC) | |
| OCLC library identifier | DEBBG |
| System control number | BV041069692 |
| 029 1# - (OCLC) | |
| OCLC library identifier | DEBBG |
| System control number | BV041911234 |
| 029 1# - (OCLC) | |
| OCLC library identifier | DKDLA |
| System control number | 820120-katalog:000655911 |
| 029 1# - (OCLC) | |
| OCLC library identifier | NLGGC |
| System control number | 372651682 |
| 029 1# - (OCLC) | |
| OCLC library identifier | NZ1 |
| System control number | 15340142 |
| 029 1# - (OCLC) | |
| OCLC library identifier | DEBBG |
| System control number | BV043395562 |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (OCoLC)828933132 |
| Canceled/invalid control number | (OCoLC)829460534 |
| -- | (OCoLC)961671411 |
| -- | (OCoLC)962584608 |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | QR76.6 |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | NAT |
| Subject category code subdivision | 022000 |
| Source | bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 589.908734 |
| Edition number | 23 |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | MAIN |
| 245 00 - TITLE STATEMENT | |
| Title | Minicircle and Miniplasmid DNA Vectors : |
| Remainder of title | The Future of Nonviral and Viral Gene Transfer / |
| Statement of responsibility, etc | edited by Martin Schleef. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) | |
| Place of publication, distribution, etc | Weinheim, Germany : |
| Name of publisher, distributor, etc | Wiley-Blackwell, |
| Date of publication, distribution, etc | ©2013. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 1 online resource (xxi, 235 pages) |
| 336 ## - | |
| -- | text |
| -- | txt |
| -- | rdacontent |
| 337 ## - | |
| -- | computer |
| -- | c |
| -- | rdamedia |
| 338 ## - | |
| -- | online resource |
| -- | cr |
| -- | rdacarrier |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE | |
| Bibliography, etc | Includes bibliographical references and index. |
| 588 0# - | |
| -- | Print version record. |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Minicircle and Miniplasmid DNA Vectors: The Future of Non-Viral and Viral Gene Transfer; Contents; List of Contributors; Perface; 1 Minicircle Patents: A Short IP Overview of Optimizing Nonviral DNA Vectors; 2 Operator-Repressor Titration: Stable Plasmid Maintenance without Selectable Marker Genes; 2.1 Introduction; 2.2 Antibiotics and Metabolic Burden; 2.3 The Mechanism of ORT; 2.4 ORT Strain Development; 2.5 ORT Miniplasmids; 2.6 DNA Vaccine and Gene Therapy Vectors; 2.7 ORT-VAC: Plasmid-Based Vaccine Delivery Using Salmonella enterica; 2.8 Recombinant Protein Expression. |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 2.9 Conclusions and Future DevelopmentsReferences; 3 Selection by RNA-RNA Interaction: Maximally Minimized Antibiotic Resistance-Free Plasmids; 3.1 Gene Therapy and DNA Vaccines: Emerging Technologies; 3.1.1 Therapeutic Plasmids: General Design Principles; 3.2 Therapeutic Plasmids: Novel Design and the Problem of Selection; 3.2.1 Replication Control of ColE1-Type Plasmids as an Alternative Selection Marker; 3.2.2 The MINIback Concept: Selection by RNA-RNA Interaction; 3.2.3 Improved Production Processes by MINIback Plasmids; 3.2.4 Improving Sequence Composition; 3.2.5 Efficient Gene Transfer. |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 3.3 ConclusionsAcknowledgments; References; 4 Plasmid-Based Medicinal Products -- Focus on pFAR: A Miniplasmid Free of Antibiotic Resistance Markers; 4.1 Introduction: Rationale for the Development of Biosafe DNA Plasmid Vectors; 4.2 Specific Requirements for the Use of DNA Product as Medicines; 4.2.1 Requirements for Plasmid Quality and Purity; 4.2.2 Requirements for the Removal of Antibiotic Resistance Markers from Plasmid DNA; 4.2.2.1 Requirements for Biosafe Plasmids; 4.2.2.2 Positive Impact on the Removal of Antibiotic Resistance Markers. |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 4.2.2.3 Effect of Plasmid Size on Gene Transfer Efficiency In Vitro and In Vivo4.3 Nonviral Gene Vectors Devoid of Antibiotic Resistance Markers; 4.3.1 Generalities; 4.3.2 Selection Systems Devoid of Antibiotic Resistance Markers; 4.3.2.1 Complementation of Host Auxotrophy by a Function-Encoded Plasmid; 4.3.2.2 The Operator-Repressor Titration (ORT) System; 4.3.2.3 Protein-Based Antidote/Poison Selection Systems; 4.3.2.4 RNA-Based Selection Marker; 4.3.2.5 Suppression of a Nonsense Mutation; 4.4 The pFAR Plasmid Family; 4.4.1 Description of the Antibiotic-Free Selection System. |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 4.4.2 pFAR Vectors Promote Efficient Expression in Several Types of Mammalian Cells4.4.2.1 In Vitro Transfection Study; 4.4.2.2 In Vivo Transfection Studies; 4.4.3 Concluding Remarks on the pFAR4 Biosafe Miniplasmid; 4.5 Concluding Remarks and Perspectives; Acknowledgments; References; 5 Plasmid DNA Concatemers: Influence of Plasmid Structure on Transfection Efficiency; 5.1 Introduction; 5.2 Plasmid DNA Topology and Size; 5.3 Plasmid DNA Concatemers; 5.4 Conclusions; Acknowledgments; References; 6 Analytical Tools in Minicircle Production; 6.1 Introduction. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc | This first title on the topic provides complete coverage, including the molecular basis, production and possible biomedical applications. Written by the most prominent academic researchers in the field as well as by researchers at one of the world's leading companies in industrial production of minicircle DNA, this practical book is aimed at everyone who is directly or indirectly involved in the development of gene therapies. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Plasmids |
| General subdivision | Genetics. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Genetic engineering. |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Plasmids. |
| 650 #4 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Gene therapy. |
| 650 #4 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Genetic engineering. |
| 650 #4 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Plasmids |
| General subdivision | Genetics. |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | NATURE |
| General subdivision | Plants |
| -- | Mushrooms. |
| Source of heading or term | bisacsh |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Genetic engineering. |
| Source of heading or term | fast |
| -- | (OCoLC)fst00940027 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Plasmids |
| General subdivision | Genetics. |
| Source of heading or term | fast |
| -- | (OCoLC)fst01066381 |
| 655 #4 - INDEX TERM--GENRE/FORM | |
| Genre/form data or focus term | Electronic books. |
| 655 #7 - INDEX TERM--GENRE/FORM | |
| Genre/form data or focus term | Electronic books. |
| Source of term | local |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Schleef, M. |
| Fuller form of name | (Martin) |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Display text | Print version: |
| Title | Minicircle and miniplasmid DNA vectors. |
| Place, publisher, and date of publication | Weinheim, Germany : Wiley-Blackwell, ©2013 |
| International Standard Book Number | 9783527324569 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://onlinelibrary.wiley.com/book/10.1002/9783527670420">http://onlinelibrary.wiley.com/book/10.1002/9783527670420</a> |
| Public note | Wiley Online Library |
| 938 ## - | |
| -- | EBL - Ebook Library |
| -- | EBLB |
| -- | EBL4044501 |
| 938 ## - | |
| -- | EBL - Ebook Library |
| -- | EBLB |
| -- | EBL1129769 |
| 938 ## - | |
| -- | ebrary |
| -- | EBRY |
| -- | ebr10662568 |
| 938 ## - | |
| -- | EBSCOhost |
| -- | EBSC |
| -- | 542862 |
| 938 ## - | |
| -- | Ingram Digital eBook Collection |
| -- | IDEB |
| -- | cis24876727 |
| 938 ## - | |
| -- | YBP Library Services |
| -- | YANK |
| -- | 10247717 |
| 938 ## - | |
| -- | YBP Library Services |
| -- | YANK |
| -- | 10350847 |
| 938 ## - | |
| -- | YBP Library Services |
| -- | YANK |
| -- | 12679557 |
| 994 ## - | |
| -- | 92 |
| -- | DG1 |
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