Successful drug discovery / (Record no. 13912)
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| fixed length control field | 04662cam a2200637Ii 4500 |
| 001 - CONTROL NUMBER | |
| control field | ocn903897512 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OCoLC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20171224114831.0 |
| 006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS--GENERAL INFORMATION | |
| fixed length control field | m o d |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr cnu|||unuuu |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 150223s2015 gw ob 001 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | DG1 |
| Language of cataloging | eng |
| Description conventions | rda |
| -- | pn |
| Transcribing agency | DG1 |
| Modifying agency | IDEBK |
| -- | COO |
| -- | CDX |
| -- | OCLCF |
| -- | RECBK |
| -- | OCLCQ |
| -- | DEBBG |
| -- | EBLCP |
| 019 ## - | |
| -- | 903317911 |
| -- | 904961652 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9783527678433 |
| Qualifying information | (electronic bk.) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 3527678433 |
| Qualifying information | (electronic bk.) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 1322949557 |
| Qualifying information | (ebk) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9781322949550 |
| Qualifying information | (ebk) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9783527678457 |
| Qualifying information | (electronic bk.) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 352767845X |
| Qualifying information | (electronic bk.) |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1002/9783527678433 |
| Source of number or code | doi |
| 028 01 - PUBLISHER NUMBER | |
| Publisher number | EB00596207 |
| Source | Recorded Books |
| 029 1# - (OCLC) | |
| OCLC library identifier | NZ1 |
| System control number | 15914892 |
| 029 1# - (OCLC) | |
| OCLC library identifier | DEBBG |
| System control number | BV043397534 |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (OCoLC)903897512 |
| Canceled/invalid control number | (OCoLC)903317911 |
| -- | (OCoLC)904961652 |
| 037 ## - SOURCE OF ACQUISITION | |
| Stock number | 726237 |
| Source of stock number/acquisition | MIL |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | RS420 |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 615.1/9 |
| Edition number | 23 |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | MAIN |
| 245 00 - TITLE STATEMENT | |
| Title | Successful drug discovery / |
| Statement of responsibility, etc | edited by János Fischer and David P. Rotella. |
| 264 #1 - | |
| -- | Weinheim, Germany : |
| -- | Wiley-VCH, |
| -- | 2015. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 1 online resource. |
| 336 ## - | |
| -- | text |
| -- | txt |
| -- | rdacontent |
| 337 ## - | |
| -- | computer |
| -- | c |
| -- | rdamedia |
| 338 ## - | |
| -- | online resource |
| -- | cr |
| -- | rdacarrier |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Part I: General Aspects. Serendipitous Target-Based Drug Discoveries / János Fischer, David P Rotella -- Drug Discoveries and Molecular Mechanism of Action / David C Swinney -- Part II: Drug Class. Insulin Analogs -- Improving the Therapy of Diabetes / John M Beals -- Part III: Case Histories. The Discovery of Stendra (Avanafil) for the Treatment of Erectile Dysfunction / Koichiro Yamada, Toshiaki Sakamoto, Kenji Omori, Kohei Kikkawa -- Dapagliflozin, A Selective SGLT2 Inhibitor for Treatment of Diabetes / William N Washburn -- Elvitegravir, A New HIV-1 Integrase Inhibitor for Antiretroviral Therapy / Hisashi Shinkai -- Discovery of Linagliptin for the Treatment of Type 2 Diabetes Mellitus / Matthias Eckhardt, Thomas Klein, Herbert Nar, Sandra Thiemann -- The Discovery of Alimta (Pemetrexed) / Edward C Taylor -- Perampanel: A Novel, Noncompetitive AMPA Receptor Antagonist for the Treatment of Epilepsy / Shigeki Hibi -- Discovery and Development of Telaprevir (Incivek): A Protease Inhibitor to Treat Hepatitis C Infection / Bhisetti G Rao, Mark Murcko, Mark J Tebbe, Ann D Kwong -- Antibody-Drug Conjugates: Design and Development of Trastuzumab Emtansine (T-DM1) / Sandhya Girish, Gail D Lewis Phillips, Fredric S Jacobson, Jagath R Junutula, Ellie Guardino. |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE | |
| Bibliography, etc | Includes bibliographical references and index. |
| 588 0# - | |
| -- | Online resource; title from PDF title page (John Wiley, viewed February 23, 2015). |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc | The first volume of the book series "Successful Drug Discovery" is focusing on new drug discoveries during the last decade, from established drugs to recently introduced drugs of all kinds:small-molecule-, peptide-, and protein-based drugs. The role of serendipity is analyzed in some very successful drugs where the research targets of the lead molecule and the drug are different. Phenotypic and target-based drug discovery approaches are discussed from the viewpoint of pioneer drugs and analogues. This volume gives an excellent overview of insulin analogues including a discussion of the properties of rapid-acting andlong-acting formulations of this important hormone. The major part of the book is devoted to case histories of new drug discoveries described by their key inventors. Eight case histories range across many therapeutic fields. The goal of this book series is to help the participants of thedrug research community with a reference book series and to support teaching in medicinal chemistry with case histories and review articles of new drugs. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Drugs |
| General subdivision | Design. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Pharmaceutical chemistry. |
| 650 #4 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Medical. |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | MEDICAL |
| General subdivision | Pharmacology. |
| Source of heading or term | bisacsh |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Drugs |
| General subdivision | Design. |
| Source of heading or term | fast |
| -- | (OCoLC)fst00898790 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Pharmaceutical chemistry. |
| Source of heading or term | fast |
| -- | (OCoLC)fst01060115 |
| 655 #4 - INDEX TERM--GENRE/FORM | |
| Genre/form data or focus term | Electronic books. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Fischer, János, |
| Relator term | editor. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Rotella, David P., |
| Relator term | editor. |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Display text | Print version: |
| International Standard Book Number | 9783527678433 |
| Record control number | (OCoLC)903897512 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://onlinelibrary.wiley.com/book/10.1002/9783527678433">http://onlinelibrary.wiley.com/book/10.1002/9783527678433</a> |
| Public note | Wiley Online Library |
| 938 ## - | |
| -- | Ingram Digital eBook Collection |
| -- | IDEB |
| -- | cis35639447 |
| 938 ## - | |
| -- | EBL - Ebook Library |
| -- | EBLB |
| -- | EBL4044562 |
| 938 ## - | |
| -- | Coutts Information Services |
| -- | COUT |
| -- | 30970594 |
| 938 ## - | |
| -- | Ingram Digital eBook Collection |
| -- | IDEB |
| -- | cis30970594 |
| 938 ## - | |
| -- | Recorded Books, LLC |
| -- | RECE |
| -- | rbeEB00596207 |
| 994 ## - | |
| -- | 92 |
| -- | DG1 |
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