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Bioinorganic medicinal chemistry / edited by Enzo Alessio.

Contributor(s): Alessio, E. (Enzo).
Material type: materialTypeLabelBookPublisher: Weinheim : Chichester : Wiley-VCH ; John Wiley [distributor], 2011Description: 1 online resource.Content type: text Media type: computer Carrier type: online resourceISBN: 9783527633104; 3527633103; 9783527633111; 3527633111; 1283370484; 9781283370486.Subject(s): Pharmaceutical chemistry | Inorganic compounds -- Therapeutic use | MEDICAL -- PharmacologyGenre/Form: Electronic books.Additional physical formats: Print version:: Bioinorganic medicinal chemistry.DDC classification: 615.2 Online resources: Wiley Online Library
Contents:
Front Matter -- Medicinal Inorganic Chemistry: State of the Art, New Trends, and a Vision of the Future / Nicola J Farrer, Peter J Sadler -- Targeting Strategies for Metal-Based Therapeutics / Julia F Norman, Trevor W Hambley -- Current Status and Mechanism of Action of Platinum-Based Anticancer Drugs / Shanta Dhar, Stephen J Lippard -- New Trends and Future Developments of Platinum-Based Antitumor Drugs / Xiaoyong Wang, Zijian Guo -- Ruthenium and Other Non-Platinum Anticancer Compounds / Ioannis Bratsos, Teresa Gianferrara, Enzo Alessio, Christian G Hartinger, Michael A Jakupec, Bernhard K Keppler -- The Challenge of Establishing Reliable Screening Tests for Selecting Anticancer Metal Compounds / Angela Boccarelli, Alessandra Pannunzio, Mauro Coluccia -- Gold-Based Therapeutic Agents: A New Perspective / Susan J Berners-Price -- MRI Contrast Agents: State of the Art and New Trends / Daniela Delli Castelli, Eliana Gianolio, Silvio Aime -- Metal-Based Radiopharmaceuticals / Roger Alberto -- Boron and Gadolinium in the Neutron Capture Therapy of Cancer / Ellen L Crossley, H Y Vincent Ching, Joseph A Ioppolo, Louis M Rendina -- Essential Metal Related Metabolic Disorders / Yasmin Mawani, Chris Orvig -- Metal Compounds as Enzyme Inhibitors / Gilles Gasser, Nils Metzler-Nolte -- Biomedical Applications of Metal-Containing Luminophores / Albert Ruggi, David N Reinhoudt, Aldrik H Velders -- Index.
Summary: This book gives a comprehensive overview about medicinal inorganic chemistry. Topics like targeting strategies, mechanism of action, Pt-based antitumor drugs, radiopharmaceuticals are covered in detail and offer the reader an in-depth overview about this important topic.
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Front Matter -- Medicinal Inorganic Chemistry: State of the Art, New Trends, and a Vision of the Future / Nicola J Farrer, Peter J Sadler -- Targeting Strategies for Metal-Based Therapeutics / Julia F Norman, Trevor W Hambley -- Current Status and Mechanism of Action of Platinum-Based Anticancer Drugs / Shanta Dhar, Stephen J Lippard -- New Trends and Future Developments of Platinum-Based Antitumor Drugs / Xiaoyong Wang, Zijian Guo -- Ruthenium and Other Non-Platinum Anticancer Compounds / Ioannis Bratsos, Teresa Gianferrara, Enzo Alessio, Christian G Hartinger, Michael A Jakupec, Bernhard K Keppler -- The Challenge of Establishing Reliable Screening Tests for Selecting Anticancer Metal Compounds / Angela Boccarelli, Alessandra Pannunzio, Mauro Coluccia -- Gold-Based Therapeutic Agents: A New Perspective / Susan J Berners-Price -- MRI Contrast Agents: State of the Art and New Trends / Daniela Delli Castelli, Eliana Gianolio, Silvio Aime -- Metal-Based Radiopharmaceuticals / Roger Alberto -- Boron and Gadolinium in the Neutron Capture Therapy of Cancer / Ellen L Crossley, H Y Vincent Ching, Joseph A Ioppolo, Louis M Rendina -- Essential Metal Related Metabolic Disorders / Yasmin Mawani, Chris Orvig -- Metal Compounds as Enzyme Inhibitors / Gilles Gasser, Nils Metzler-Nolte -- Biomedical Applications of Metal-Containing Luminophores / Albert Ruggi, David N Reinhoudt, Aldrik H Velders -- Index.

This book gives a comprehensive overview about medicinal inorganic chemistry. Topics like targeting strategies, mechanism of action, Pt-based antitumor drugs, radiopharmaceuticals are covered in detail and offer the reader an in-depth overview about this important topic.

Print version record.

Includes bibliographical references and index.

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