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Development of Vaccines : From Discovery to Clinical Testing / edited by Manmohan Singh, Indresh K. Srivasta.

Contributor(s): Manmohan Singh, 1964 November 8- | Srivasta, Indresh K.
Material type: materialTypeLabelBookPublisher: Hoboken, N.J. : John Wiley & Sons, ©2011Description: 1 online resource (xiii, 454 pages) : illustrations (some color).Content type: text Media type: computer Carrier type: online resourceISBN: 9781118023648; 1118023641; 9781118023624; 1118023625; 9781118023631; 1118023633.Subject(s): Vaccines | Drug development | Drug stability | MEDICAL -- Pharmacology | Drug development | Drug stability | Vaccines | Vaccines -- pharmacology | Drug Discovery -- methods | Drug StabilityGenre/Form: Electronic books.Additional physical formats: Print version:: Development of vaccines.DDC classification: 615/.372 Online resources: Wiley Online Library
Contents:
Microbial vaccines design : the reverse vaccinology approach / Roberto Rosini, Michele A. Barocchi, Rino Rappuoli -- Design and development of recombinant vaccines with viral properties / Gerd Lipowsky, Martin F. Bachmann -- Tools for vaccine design : prediction and validation of highly immunogenic and conserved class II epitopes, and development of epitope-driven vaccines / Anne S. De Groot [and others] -- Virus like-particle vaccines advantages and challenges / Ted M. Ross [and others] -- Design platforms of nanocapsules for human therapeutics or vaccines / Masaaki Kawano [and others] -- Designing immunogens for vaccine development in reference to HIV / Aemro Kassa [and others].
Expression and purification of recombinant proteins for vaccine applications / Carlo Zambonelli, Deeann Martinez-Guzmann, and Indresh K. Srivastava -- DNA vaccines for infectious diesase / Samuel Stepenson, Manmohan Singh, Indresh K. Srivastava -- Developing stable cell lines for the production of vaccine antigens / Xiaotian Zhong [and others] -- Spectroscopy of vaccines / C. Russell Middaugh, Sangeeta B. Joshi -- Biophysical characterization of protein antigens within vaccine formulations / Padima Malyala, Derek O'Hagan, Manmohan Singh -- Structural characteristics predict the stability of HIV / Zohar Biron [and others] -- Selection of optimal adjuvants and product factors that affect vaccine immunogenicity / Wei Wang, Manmohan Singh -- Lyophilization and stabilization of vaccines / James Chesko [and others] -- Effect of buffers and stabilizers on vaccine stability and efficacy / Shireesh P. Apte, Sydney Ugwu -- Selection of final product containers / Luis Baez, Adrian Distler -- From the lab to the clinic : filing a phase I IND for an investigational vaccine / Kenneth G. Surowitz.
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Includes bibliographical references and index.

Microbial vaccines design : the reverse vaccinology approach / Roberto Rosini, Michele A. Barocchi, Rino Rappuoli -- Design and development of recombinant vaccines with viral properties / Gerd Lipowsky, Martin F. Bachmann -- Tools for vaccine design : prediction and validation of highly immunogenic and conserved class II epitopes, and development of epitope-driven vaccines / Anne S. De Groot [and others] -- Virus like-particle vaccines advantages and challenges / Ted M. Ross [and others] -- Design platforms of nanocapsules for human therapeutics or vaccines / Masaaki Kawano [and others] -- Designing immunogens for vaccine development in reference to HIV / Aemro Kassa [and others].

Expression and purification of recombinant proteins for vaccine applications / Carlo Zambonelli, Deeann Martinez-Guzmann, and Indresh K. Srivastava -- DNA vaccines for infectious diesase / Samuel Stepenson, Manmohan Singh, Indresh K. Srivastava -- Developing stable cell lines for the production of vaccine antigens / Xiaotian Zhong [and others] -- Spectroscopy of vaccines / C. Russell Middaugh, Sangeeta B. Joshi -- Biophysical characterization of protein antigens within vaccine formulations / Padima Malyala, Derek O'Hagan, Manmohan Singh -- Structural characteristics predict the stability of HIV / Zohar Biron [and others] -- Selection of optimal adjuvants and product factors that affect vaccine immunogenicity / Wei Wang, Manmohan Singh -- Lyophilization and stabilization of vaccines / James Chesko [and others] -- Effect of buffers and stabilizers on vaccine stability and efficacy / Shireesh P. Apte, Sydney Ugwu -- Selection of final product containers / Luis Baez, Adrian Distler -- From the lab to the clinic : filing a phase I IND for an investigational vaccine / Kenneth G. Surowitz.

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