TY - BOOK AU - Peng,Bo AU - Kimmel,Marek AU - Amos,Christopher I. TI - Forward-Time Population Genetics Simulations: Methods, Implementation, and Applications SN - 9781118180327 AV - QH455 .P464 2012eb U1 - 576.5/8 23 PY - 2012/// CY - Hoboken, N.J. PB - Wiley Blackwell KW - Population genetics KW - Evolution (Biology) KW - Computer simulation KW - Genetics, Population KW - Biological Evolution KW - Computer Simulation KW - Models, Genetic KW - SCIENCE KW - Life Sciences KW - Genetics & Genomics KW - bisacsh KW - fast KW - Electronic books KW - local N1 - Includes bibliographical references and index; Frontmatter -- Basic Concepts and Models -- Simulation of Population Genetics Models -- Ascertainment Bias in Population Genetics -- Observing Properties of Evolving Populations -- Simulating Populations with Complex Human Diseases -- Nonrandom Mating and its Applications -- Appendix: Forward-Time Simulations Using simuPOP -- Index; Basic concepts and models -- Simulation of population genetics models -- Ascertainment bias in population genetics -- Observing properties of evolving populations -- Simulating populations with complex human diseases -- Nonrandom mating and its applications N2 - The rapid increase of the power of personal computers has led to the use of serious simulation programs such as easy POP in genetic studies. This book summarizes recent advances in forward-time simulation methods and demonstrates their applications in population genetics and genetic epidemiology. The authors introduce commonly used forward-time population genetics simulation methods, including some new methods, and introduce a forward-time population genetics simulation environment, simuPOP, as a powerful and flexible tool to implement these simulations. Researchers and students in population and statistical genetics will find this book useful UR - http://onlinelibrary.wiley.com/book/10.1002/9781118180358 ER -