TY - BOOK AU - Kontush,Anatol AU - Chapman,M.John TI - High-Density Lipoproteins: Structure, Metabolism, Function, and Therapeutics SN - 9781118158647 AV - QP552.L5 .H55 2012eb U1 - 572/.68 23 PY - 2012/// CY - Hoboken, N.J. PB - John Wiley & Sons, Inc. KW - High density lipoproteins KW - Metabolism KW - Cardiovascular system KW - Diseases KW - Treatment KW - Lipoproteins, HDL KW - metabolism KW - Arteriosclerosis KW - physiopathology KW - Cardiovascular Diseases KW - therapy KW - Lipoproteïnes de densitat alta KW - Metabolisme KW - Sistema cardiovascular KW - Malalties KW - Tractament KW - Lipoproteïnes KW - Aterosclerosi KW - SCIENCE KW - Life Sciences KW - Biochemistry KW - bisacsh KW - fast KW - Electronic books KW - Llibres electrònics KW - local N1 - Includes bibliographical references and index; Normal functional HDL -- Functionally defective HDL -- Therapeutic normalisation of subnormal levels and defective biological activities of HDL N2 - A complete guide to the role of high-density lipoproteins (HDL) in new and emerging therapies With high-density lipoproteins (HDL) playing an increasing role in cardiovascular disease prevention, there is a growing need for an in-depth look at HDL and its clinical value. This book summarizes the current state of knowledge in the field, providing for the first time a comprehensive, systematic, stylistically coherent, and up-to-date review of the composition, structure, heterogeneity, metabolism, epidemiology, genetics, and function of HDL. Divided into three main parts, High-Density Lipoproteins first examines normal HDL particles, then describes defective HDL, and finally addresses the therapeutic normalization of subnormal levels and defective biological activities of this lipoprotein class. The book highlights the functional properties of HDL, which are relevant to the pathophysiology of atherosclerosis and thrombosis, and discusses the compositional and metabolic heterogeneity of HDL particles. Readers will come away with a clear understanding of the role of HDL in biological processes, the potential value of functional HDL as a therapeutic target, and how current and emerging therapies are poised to influence the treatment of heart disease in the future UR - http://onlinelibrary.wiley.com/book/10.1002/9781118158678 ER -