TY  - BOOK
AU  - Brenna,Elisabetta
TI  - Synthetic methods for biologically active molecules: exploring the potential of bioreductions 
SN  - 9783527665785
AV  - QD461 
U1  - 548.478 
PY  - 2013///
CY  - Weinheim, Germany
PB  - Wiley-VCH
KW  - Reduction (Chemistry)
KW  - Bioactive compounds
KW  - Synthesis
KW  - Enzymes
KW  - Biotechnology
KW  - Industrial applications
KW  - SCIENCE
KW  - Physics
KW  - Crystallography
KW  - bisacsh
KW  - Biochemistry
KW  - fast
KW  - Biomolecules
KW  - Electronic books
N1  - Includes bibliographical references and index; Development of Sustainable Biocatalytic Reduction Processes for Organic Chemists / Roland Wohlgemuth -- Reductases: From Natural Diversity to Established Biocatalysis and to Emerging Enzymatic Activities / Elena Fernández-Álvaro, Pablo Domínguez de María -- Synthetic Strategies Based on C=C Bioreductions for the Preparation of Biologically Active Molecules / Francesco G Gatti, Fabio Parmeggiani, Alessandro Sacchetti -- Synthetic Strategies Based on C=O Bioreductions for the Preparation of Biologically Active Molecules / Aníbal Cuetos, Alba Díaz-Rodríguez, Iván Lavandera -- Protein Engineering: Development of Novel Enzymes for the Improved Reduction of C=C Double Bonds / Sabrina Kille, Manfred T Reetz -- Protein Engineering: Development of Novel Enzymes for the Improved Reduction of C=O Double Bonds / Nobuya Itoh, Yoshihide Makino -- Synthetic Applications of Aminotransferases for the Preparation of Biologically Active Molecules / Sachin Pannuri, Sanjay Kamat, Abraham R Mártin-García -- Strategies for Cofactor Regeneration in Biocatalyzed Reductions / Selin Kara, Joerg H Schrittwieser, Frank Hollmann -- Solvent Effects in Bioreductions / Yan Ni, Hui-Lei Yu, Jian-He Xu -- Application of Product Removal (ISPR) Technologies for Implementation and Scale-Up of Biocatalytic Reductions / John M Woodley -- Bioreductions in Multienzymatic One-Pot and Cascade Processes / Daniela Monti, Erica E Ferrandi -- Dynamic Kinetic Resolutions Based on Reduction Processes / Dimitris Kalaitzakis, Ioulia Smonou -- Relevant Practical Applications of Bioreduction Processes in the Synthesis of Active Pharmaceutical Ingredients / Gábor Tasnádi, Mélanie Hall
N2  - This ready reference focuses on the currently available toolbox of biocatalysed reductions of C=O, C=C and formal C=N double bonds to show which transformations are reliable for use in manufacturing processes and which still require improvements and investigation. Following an introductory chapter, chapters 2-4 present the synthetic strategies which are currently available for the reduction of C=C, C=O and for reductive amination, by means of whole cell catalysts and isolated enzymes
UR  - http://onlinelibrary.wiley.com/book/10.1002/9783527665785
ER  -