TY - BOOK AU - Tompa,Peter TI - Structure and function of intrinscially disordered proteins SN - 9781420078930 (ebook : PDF) PY - 2010/// CY - Boca Raton PB - Chapman & Hall/CRC Press KW - Proteins KW - Pathophysiology KW - Structure-activity relationships KW - Metabolism KW - Disorders KW - Electronic books KW - lcsh N1 - "A Chapman & Hall book."; Includes bibliographical references (p. 265-312) and index; Principles of protein structure and function -- A brief history of protein disorder -- Indirect techniques for recognizing and characterizing protein disorder -- Hydrodynamic techniques -- Spectroscopic techniques for characterizing disorder -- Nuclear magnetic resonance -- Proteomic approaches for the identification of IDPs -- IDPs under conditions approaching in vivo -- Prediction of disorder -- Structure of IDPs -- Biological processes enriched in disorder -- Molecular functions of disordered proteins -- Evolution and prevalence of disorder -- Extension of the structure-function paradigm -- Structural disorder and disease; Also available in print edition UR - http://marc.crcnetbase.com/isbn/9781420078930 ER -