TY - BOOK AU - You,Guofeng AU - Morris,Marilyn Emily TI - Drug transporters: molecular characterization and role in drug disposition T2 - Wiley series in drug discovery and development SN - 9781118705049 (pdf) AV - R857.B52 U1 - 571.6/4 PY - 2014///] CY - Hoboken, New Jersey PB - John Wiley & Sons, Inc. KW - Carrier proteins KW - Drug carriers (Pharmacy) KW - SCIENCE KW - Life Sciences KW - Anatomy & Physiology KW - bisacsh KW - fast KW - Biological Transport KW - physiology KW - Membrane Transport Proteins KW - Pharmacokinetics KW - Pharmakokinetik KW - gnd KW - Arzneimittel KW - Chemische Synthese KW - Arzneimittelwechselwirkung KW - Electronic books N1 - Includes bibliographical references and index; Overview of drug transporter families -- Organic Cation and Zwitterion transporters OCT, OCTN -- Organic anion transporters OAT -- Organic anion transporting polypeptides OATP -- Mammalian peptide transporters PEPT -- The monocarboxylate transporters MCT -- The nucleoside transporters CNT, ENT -- Bile acid transporters -- Multidrug resistance protein P-glycoprotein -- Multidrug resistance-associated proteins MRP -- Breast cancer resistance protein BCRP -- Multidrug and toxin extrusion proteins MATE -- Drug transport in the liver -- Drug transport in the brain -- Drug transport in the kidney -- Drug transport in the intestine -- Drug transport in the placenta -- Experimental approaches to studying drug transport -- Transporters in drug discovery in silico approaches -- Polymorphisms of drug transporters and clinical relevance -- Diet/nutrient interactions with drug transporters -- Clinical relevance drug-drug interactions, pharmacokinetics, pharmacodynamics and toxicity -- Regulatory science perspectives on transporter studies in drug development UR - http://onlinelibrary.wiley.com/book/10.1002/9781118705308 ER -