TY - BOOK AU - DeFronzo,Ralph A. AU - Ferrannini,Eleuterio AU - Alberti,K.G.M.M. AU - Zimmet,Paul TI - International textbook of diabetes mellitus SN - 9781118387672 (ePub) AV - RC660 U1 - 616.4/62 23 PY - 2015/// CY - Chichester, West Sussex, Hoboken, NJ PB - John Wiley & Sons Inc. KW - Diabetes KW - HEALTH & FITNESS / Diseases / General KW - bisacsh KW - MEDICAL / Clinical Medicine KW - MEDICAL / Diseases KW - MEDICAL / Evidence-Based Medicine KW - MEDICAL / Internal Medicine KW - fast KW - Medical KW - Diabetes Mellitus KW - Electronic books N1 - Includes bibliographical references and index; ""Title Page""; ""Section Editors""; ""Copyright""; ""Table of Contents""; ""Contributors""; ""Preface""; ""Section I: Epidemiology""; ""Chapter 1: Classification of diabetes mellitus and other categories of glucose intolerance""; ""Introduction""; ""Historical perspective and current classifications""; ""Type 1 process""; ""Type 2 process""; ""Other specific types""; ""Classification of genetic disorders""; ""Diabetes in children and youth""; ""Diagnosis of diabetes using HbA1c""; ""Diagnosis of gestational diabetes mellitus""; ""Impaired glucose regulation (impaired glucose tolerance and impaired fasting glycemia)""""Normoglycemia""; ""Summary""; ""References""; ""Chapter 2: Epidemiology and risk factors for type 1 diabetes mellitus""; ""Introduction""; ""Prevalence and incidence""; ""β-Cell autoimmunity and risk factors""; ""Established type 1 diabetes""; ""References""; ""Chapter 3: Epidemiology and geography of type 2 diabetes mellitus""; ""Age- and sex-specific prevalence of type 2 diabetes in different ethnic groups""; ""Prevalence of impaired glucose tolerance and impaired fasting glycemia in different ethnic groups""""Sex differences in prevalence of diabetes, IGT, and IFG""; ""The ratio of IGT to diabetes""; ""Secular trends in prevalence of type 2 diabetes""; ""Type 2 diabetes in children""; ""Modifiable risk factors for type 2 diabetes""; ""Nontraditional modifiable risk factors for type 2 diabetes""; ""References""; ""Section II: Physiology of pancreatic function""; ""Chapter 4: Development and maintenance of the islet β cell""; ""Introduction""; ""Pancreas development""; ""Cytodifferentiation in the developing pancreas""""Postnatal β-cell growth and maintenance""; ""Conclusions and areas of future study""; ""References""; ""Chapter 5: Pancreatic morphology in normal and diabetic states""; ""Pancreatic anatomy and morphology""; ""Islet composition and morphology""; ""Islet β cell regenerative potential""; ""Disturbances in pancreas/islet morphology in diabetes""; ""Mechanisms of β-cell loss in type 2 diabetes""; ""Summary and future directions""; ""Acknowledgments""; ""References""; ""Chapter 6: Insulin gene expression and biosynthesis""; ""Introduction""; ""Insulin gene expression""""Insulin biosynthesis""; ""Acknowledgments""; ""References""; ""Chapter 7: β-Cell biology of insulin secretion""; ""Introduction""; ""β-Cell metabolism""; ""Metabolism-secretion coupling""; ""Dynamics of insulin secretion""; ""Modulation of insulin secretion by various intracellular signals""; ""Pathophysiology of pancreatic β cells""; ""Conclusions""; ""References""; ""Chapter 8: Normal β-cell function""; ""Introduction""; ""Methods for the Assessment of Insulin Secretion""; ""β-Cell Response to Intravenous Glucose""; ""β-Cell Response to Oral Glucose"" N2 - The International Textbook of Diabetes Mellitus has been a successful, well-respected medical textbook for almost 20 years, over 3 editions. Encyclopaedic and international in scope, the textbook covers all aspects of diabetes ensuring a truly multidisciplinary and global approach. Sections covered include epidemiology, diagnosis, pathogenesis, management and complications of diabetes and public health issues worldwide UR - http://onlinelibrary.wiley.com/book/10.1002/9781118387658 ER -