Brain diseases and metalloproteins [electronic resource] / edited by David R. Brown.

Includes bibliographical references and index.

1. Introduction / David R. Brown -- 2. A possible key role for redox-active metal ions and soluble oligomers in neurodegenerative disease / Brian J. Tabner ... [et al.] -- 3. Modelling of the metal binding sites in proteins involved in neurodegeneration / Ewa Gralka ... [et al.] -- 4. Mammalian metallothioneins / Duncan E. K. Sutherland and Martin J. Stillman -- 5. Copper transporting P-type ATPases in the brain / Sharon La Fontaine, James Camakaris, and Julian Mercer -- 6. Role of the amyloid precursor protein and copper in Alzheimer's disease / Loredana Spoerri ... [et al.] -- 7. Role of aluminum and other metal ions in the pathogenesis of Alzheimer's disease / Silvia Bolognin and Paolo Zatta -- 8. Prion diseases, metals and antioxidants / Paul Davies and David R. Brown -- 9. Emerging role for copper-bound [alpa]-synuclein in Parkinson's disease etiology / Heather R. Lucas and Jennifer C. Lee -- 10. Interactions of [alpha]-synuclein with metal ions : new insights into the structural biology and bioinorganic chemistry of Parkinson's disease / Andr�es Binolfi and Claudio O. Fern�andez -- 11. An attempt to treat amyotrophic lateral sclerosis by intracellular copper modification using ammonium tetrathiomolybdate and/or metallothionein : fundamentals and perspective / Shin-Ichi Ono ... [et al

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