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Modern methods in stereoselective aldol reactions / edited by Rainer Mahrwald.

Contributor(s): Material type: TextTextPublication details: Weinheim : Wiley-VCH, ©2013.Description: 1 online resource (xiv, 536 pages) : illustrationsContent type:
  • text
Media type:
  • computer
Carrier type:
  • online resource
ISBN:
  • 9783527656714
  • 3527656715
  • 9783527656745
  • 352765674X
  • 9783527656738
  • 3527656731
  • 9783527656721
  • 3527656723
Subject(s): Genre/Form: Additional physical formats: Print version:: Modern methods in stereoselective aldol reactions.DDC classification:
  • 547.036 23
LOC classification:
  • QD281.C7 M63 2013
Online resources:
Contents:
Stereoselective Acetate Aldol Reactions / Pedro Romea, Fèlix Urpí -- The Vinylogous Mukaiyama Aldol Reaction in Natural Product Synthesis / Martin Cordes, Markus Kalesse -- Organocatalyzed Aldol Reactions / Gabriela Guillena -- Supersilyl Protective Groups in Aldol Reactions / Patrick B Brady, Hisashi Yamamoto -- Asymmetric Induction in Aldol Additions / Luiz C Dias, Ellen C Polo, Emílio C de Lucca, Marco A B Ferreira -- Polypropionate Synthesis via Substrate-Controlled Stereoselective Aldol Couplings of Chiral Fragments / Dale E Ward -- Application of Oxazolidinethiones and Thiazolidinethiones in Aldol Additions / Michael T Crimmins -- Enzyme-Catalyzed Aldol Additions / Pere Clapés, Jesús Joglar.
Summary: This sequel to the highly successful and much appreciated "Modern Aldol Reactions" continues to provide a systematic overview of methodologies for installing a required configuration during an aldol addition step, but shifts the focus so as to cover the latest developments. As such, it presents a set of brand new tools, including vinylogous Mukaiyama-aldol reactions, substrate-controlled aldol reactions and asymmetric induction in aldol additions. Furthermore, novel developments in existing stereoselective aldol additions are described, such as the deployment of supersilyl groups or organocatalyzed aldol additions. Throughout, all of these methodologies are presented in the context of their deployment in total synthesis of natural products.
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Print version record.

This sequel to the highly successful and much appreciated "Modern Aldol Reactions" continues to provide a systematic overview of methodologies for installing a required configuration during an aldol addition step, but shifts the focus so as to cover the latest developments. As such, it presents a set of brand new tools, including vinylogous Mukaiyama-aldol reactions, substrate-controlled aldol reactions and asymmetric induction in aldol additions. Furthermore, novel developments in existing stereoselective aldol additions are described, such as the deployment of supersilyl groups or organocatalyzed aldol additions. Throughout, all of these methodologies are presented in the context of their deployment in total synthesis of natural products.

Includes bibliographical references and index.

Stereoselective Acetate Aldol Reactions / Pedro Romea, Fèlix Urpí -- The Vinylogous Mukaiyama Aldol Reaction in Natural Product Synthesis / Martin Cordes, Markus Kalesse -- Organocatalyzed Aldol Reactions / Gabriela Guillena -- Supersilyl Protective Groups in Aldol Reactions / Patrick B Brady, Hisashi Yamamoto -- Asymmetric Induction in Aldol Additions / Luiz C Dias, Ellen C Polo, Emílio C de Lucca, Marco A B Ferreira -- Polypropionate Synthesis via Substrate-Controlled Stereoselective Aldol Couplings of Chiral Fragments / Dale E Ward -- Application of Oxazolidinethiones and Thiazolidinethiones in Aldol Additions / Michael T Crimmins -- Enzyme-Catalyzed Aldol Additions / Pere Clapés, Jesús Joglar.

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