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Solid-phase organic synthesis : concepts, strategies, and applications / edited by Patrick H. Toy, Yulin Lam.

Contributor(s): Material type: TextTextPublication details: Hoboken, N.J. : Wiley, ©2012.Description: 1 online resource (xx, 536 pages) : illustrations (some color)Content type:
  • text
Media type:
  • computer
Carrier type:
  • online resource
ISBN:
  • 9781118141649
  • 1118141644
  • 9781118141625
  • 1118141628
  • 1283409577
  • 9781283409575
Subject(s): Genre/Form: Additional physical formats: Print version:: No titleDDC classification:
  • 547/.2 23
LOC classification:
  • QD262 .S584 2012eb
Online resources:
Contents:
Linker Strategies in Modern Solid-Phase Organic Synthesis / Peter J.H. Scott -- Colorimetric Test for Solid-Phase Organic Synthesis / Yan Teng and Patrick H. Toy -- Practical Aspects of Combinatorial Solid-Phase Synthesis / Jan Hlavác, Miroslav Soural and Viktor Krchnák -- Diversity-Oriented Synthesis / Kieron M.G. O'Connell, Warren R.J.D Galloway, Brett M. Ibbeson, Albert Isidro-Llobet, Cornelius J. O'Connor and David R. Spring -- Diversity-Oriented Synthesis of Privileged Heterocycles Using Divergent Strategy / Seung Bum Park and Jonghoon Kim -- Chemo- and Regioselectivity Enhancement in Solid-Supported Reactions / Douglas D. Young and Alexander Deiters -- Asymmetric Synthesis on Solid Support / Baburaj Baskar and Kamal Kumar -- Recent Advances in Microwave-Assisted Solid-Phase Synthesis of Heterocycles / Prasad Appukkuttan, Vaibhav P. Mehta and Erik Van der Eycken -- Solid-Phase Synthesis of Heterocycles from Peptides and Amino Acids / Zhi Li, Marc Giulianotti, Wenteng Chen, Richard A. Houghten and Yongping Yu -- Generation of Drug-Like Five-Membered Heterocyclic Libraries Using Carbon Disulfide and Merrifield Resin / Young-Dae Gong and Taeho Lee -- Recent Advances in Solid-Phase 1,3-Dipolar Cycloaddition Reactions / Kirsi Harju and Jari Yli-Kauhaluoma -- Sulfones in Solid-Phase Heterocycle Synthesis / Chai Hoon Soh and Yulin Lam -- Solid-Phase Organic Radiosynthesis / Raphaël Hoareau and Peter J.H. Scott -- Solid-Phase Synthesis of Dyes and their Application as Sensors and Bioimaging Probes / Marc Vendrell, Hyung-Ho Ha, Sung Chan Lee and Young-Tae Chang -- Dendritic Molecules on Solid Support: Solid-Phase Synthesis and Applications / Kerem Goren and Moshe Portnoy -- Oligosaccharide Synthesis on Solid, Soluble Polymer, and Tag Supports / Katsunori Tanaka and Koichi Fukase.
Summary: Presents both the fundamental concepts and the most recent applications in solid-phase organic synthesisWith its emphasis on basic concepts, Solid-Phase Organic Synthesis guides readers through all the steps needed to design and perform successful solid-phase organic syntheses. The authors focus on the fundamentals of heterogeneous supports in the synthesis of organic molecules, explaining the use of a solid material to facilitate organic synthesis. This comprehensive text not only presents the fundamentals, but also reviews the most recent research findings and applications, offering readers.
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Includes bibliographical references and index.

Linker Strategies in Modern Solid-Phase Organic Synthesis / Peter J.H. Scott -- Colorimetric Test for Solid-Phase Organic Synthesis / Yan Teng and Patrick H. Toy -- Practical Aspects of Combinatorial Solid-Phase Synthesis / Jan Hlavác, Miroslav Soural and Viktor Krchnák -- Diversity-Oriented Synthesis / Kieron M.G. O'Connell, Warren R.J.D Galloway, Brett M. Ibbeson, Albert Isidro-Llobet, Cornelius J. O'Connor and David R. Spring -- Diversity-Oriented Synthesis of Privileged Heterocycles Using Divergent Strategy / Seung Bum Park and Jonghoon Kim -- Chemo- and Regioselectivity Enhancement in Solid-Supported Reactions / Douglas D. Young and Alexander Deiters -- Asymmetric Synthesis on Solid Support / Baburaj Baskar and Kamal Kumar -- Recent Advances in Microwave-Assisted Solid-Phase Synthesis of Heterocycles / Prasad Appukkuttan, Vaibhav P. Mehta and Erik Van der Eycken -- Solid-Phase Synthesis of Heterocycles from Peptides and Amino Acids / Zhi Li, Marc Giulianotti, Wenteng Chen, Richard A. Houghten and Yongping Yu -- Generation of Drug-Like Five-Membered Heterocyclic Libraries Using Carbon Disulfide and Merrifield Resin / Young-Dae Gong and Taeho Lee -- Recent Advances in Solid-Phase 1,3-Dipolar Cycloaddition Reactions / Kirsi Harju and Jari Yli-Kauhaluoma -- Sulfones in Solid-Phase Heterocycle Synthesis / Chai Hoon Soh and Yulin Lam -- Solid-Phase Organic Radiosynthesis / Raphaël Hoareau and Peter J.H. Scott -- Solid-Phase Synthesis of Dyes and their Application as Sensors and Bioimaging Probes / Marc Vendrell, Hyung-Ho Ha, Sung Chan Lee and Young-Tae Chang -- Dendritic Molecules on Solid Support: Solid-Phase Synthesis and Applications / Kerem Goren and Moshe Portnoy -- Oligosaccharide Synthesis on Solid, Soluble Polymer, and Tag Supports / Katsunori Tanaka and Koichi Fukase.

Presents both the fundamental concepts and the most recent applications in solid-phase organic synthesisWith its emphasis on basic concepts, Solid-Phase Organic Synthesis guides readers through all the steps needed to design and perform successful solid-phase organic syntheses. The authors focus on the fundamentals of heterogeneous supports in the synthesis of organic molecules, explaining the use of a solid material to facilitate organic synthesis. This comprehensive text not only presents the fundamentals, but also reviews the most recent research findings and applications, offering readers.

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