000 | 06794cam a2200877Ka 4500 | ||
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001 | ocn761318487 | ||
003 | OCoLC | ||
005 | 20171224113739.0 | ||
006 | m o d | ||
007 | cr cn||||||||| | ||
008 | 111117s2011 njua ob 001 0 eng d | ||
010 | _z 2010045225 | ||
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019 |
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_a9781118023150 _q(electronic bk.) |
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_a9781118023136 _q(electronic bk.) |
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_a1118023137 _q(electronic bk.) |
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020 | _z0470433523 | ||
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024 | 8 | _a9786613239716 | |
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_a(OCoLC)761318487 _z(OCoLC)748534063 _z(OCoLC)748937826 _z(OCoLC)757394637 _z(OCoLC)811493615 _z(OCoLC)816859624 _z(OCoLC)961631468 _z(OCoLC)962609686 |
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037 |
_a10.1002/9781118023150 _bWiley InterScience _nhttp://www3.interscience.wiley.com |
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050 | 4 |
_aRM302.7 _b.D784 2011eb |
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_a615/.19 _222 |
049 | _aMAIN | ||
245 | 0 | 0 |
_aDrug discrimination : _bapplications to medicinal chemistry and drug studies / _cedited by Richard A. Glennon, Virginia Commonwealth University, Richard Young, Virginia Commonwealth University. |
260 |
_aHoboken, N.J. : _bWiley, _c©2011. |
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300 |
_a1 online resource (xx, 510 pages) : _billustrations |
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336 |
_atext _btxt _2rdacontent |
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337 |
_acomputer _bc _2rdamedia |
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338 |
_aonline resource _bcr _2rdacarrier |
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505 | 0 | _aFrontmatter -- Color Plates -- Part I. Part Introduction -- An Introduction to Drug Discrimination -- Methodological Considerations -- Drug Discrimination: Practical Considerations -- Role of Stereochemistry in Drug Discrimination Studies -- Drug Discrimination and In Vivo Structure₆Activity Relationships -- Drug Discrimination and Mechanisms of Drug Action -- Drug Discrimination and Development of Novel Agents and Pharmacological Tools -- Appendix -- Part II. Part Introduction -- Perceptual Drug Discriminative Aspects of the Endocannabinoid Signaling System in Animals And Man / Torbj̲rn U C J̃rbe -- Discriminative Stimulus Properties of Receptor Antagonists / Joseph H Porter -- The Discrimination of Drug Mixtures / Ian P Stolerman -- Making the Right Choice: Lessons From Drug Discrimination for Research on Drug Reinforcement And Drug Self-Administration / S Stevens Negus, Matthew L Banks -- Inhalant Drug Discrimination: Methodology, Literature Review and Future Directions / Keith L Shelton, Robert L Balster -- Drug Discrimination Studies in Rhesus Monkeys: Drug Dependence and Withdrawal / Jun-Xu Li, Lisa R Gerak, Charles P France -- Human Drug Discrimination: Methodological Considerations and Application to Elucidating the Neuropharmacology of Amphetamines / Craig R Rush, Andrea R Vansickel, William W Stoops -- Nicotine Discrimination in Humans / Kenneth A Perkins -- Drug Discrimination: A Perspective / Francis C Colpaert -- Index. | |
504 | _aIncludes bibliographical references and index. | ||
505 | 0 | _aAn introduction to drug discrimination -- Methodological considerations -- Drug discrimination : practical considerations? -- Role of stereochemistry in drug discrimination studies -- Drug discrimination and in vivo structure-activity relationships -- Drug discrimination and mechanisms of drug action -- Drug discrimination and development of novel agents and pharmacological tools -- Perceptual drug discriminative aspects of the endocannabinoid signaling system in animals and man -- Discriminative stimulus properties of receptor antagonists -- The discrimination of drug mixtures -- Making the right choice : lessons from drug discrimination for research on drug reinforcement and drug self-administration -- Inhalant drug discrimination: methodology, literature review, and future directions -- Drug discrimination studies in rhesus monkeys : drug dependence and withdrawal -- Human drug discrimination : methodological considerations and application to elucidating the neuropharmacology of amphetamines -- Nicotine discrimination in humans -- Drug discrimination : a perspective. | |
520 | _aAlthough somewhat labor intensive, Drug Discrimination (DD) is of enormous applicability to the understanding of drug action. Drug Discrimination: Applications to Medicinal Chemistry and Drug Studies covers the practical applications of drug discrimination studies for medicinal chemistry, including strengths and limitations versus other pharmacological methods for evaluating drug action. The book provides medicinal chemists with a fuller understanding of the nature and use of drug discrimination studies for evaluating the action of drugs while helping pharmacologists understand and better interact with medicinal chemists and drug designers when sharing pharmacologic data. | ||
588 | 0 | _aPrint version record. | |
650 | 0 | _aDrug discrimination (Pharmacology) | |
650 | 7 |
_aMEDICAL _xDrug Guides. _2bisacsh |
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650 | 7 |
_aMEDICAL _xNursing _xPharmacology. _2bisacsh |
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650 | 7 |
_aMEDICAL _xPharmacology. _2bisacsh |
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650 | 7 |
_aMEDICAL _xPharmacy. _2bisacsh |
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650 | 7 |
_aDrug discrimination (Pharmacology) _2fast _0(OCoLC)fst00898672 |
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650 | 2 | _aPharmacological Phenomena. | |
650 | 2 |
_aDiscrimination (Psychology) _xdrug effects. |
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650 | 2 |
_aDiscrimination Learning _xdrug effects. |
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650 | 2 | _aDrug Discovery. | |
655 | 4 | _aElectronic books. | |
700 | 1 |
_aGlennon, Richard A., _d1945- |
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700 | 1 |
_aYoung, Richard, _d1952 October 24- |
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710 | 2 | _aWiley InterScience (Online service) | |
776 | 0 | 8 |
_iPrint version: _tDrug discrimination. _dHoboken, New Jersey : Wiley, ©2011 _z9781118023136 _w(OCoLC)757394637 |
856 | 4 | 0 |
_uhttp://onlinelibrary.wiley.com/book/10.1002/9781118023150 _zWiley Online Library |
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