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020 _a9781118116494
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037 _a10.1002/9781118116494
_bWiley InterScience
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049 _aMAIN
245 0 0 _aPharmacogenetics and individualized therapy /
_cedited by Anke-Hilse Maitland-van der Zee, Ann K. Daly.
260 _aHoboken, N.J. :
_bJohn Wiley & Sons,
_c©2011.
300 _a1 online resource (xi, 489 pages) :
_billustrations
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _adata file
_2rda
380 _aBibliography
504 _aIncludes bibliographical references and index.
505 0 _aPharmacogenetics : a historical perspective / A.K. Daly -- Pharmacogenetics in drug metabolism : role of phase I enzymes / V. Dolzan -- Pharmacogenetics of phase II drug metabolizing enzymes / I. Cascorbi -- Pharmacogenetics of drug transporters / Henriette E. Meyer zu Schwabedissen, Markus Grube, Heyo K. Kroemer -- Pharmacogenetics of drug targets / M. Arranz and A. Daly -- Cardiovascular pharmacogenetics / Bas J.M. Peters [and others] -- Pharmacogenetics in psychiatry / Evangelia M. Tsapakis [and others] -- Pharmacogenetics in cancer / S. Marsh -- Pharmacogenetics of asthma and COPD / E. Koster [and others] -- Pharmacogenetics of adverse drug reactions / Ann K Daly, Martin Armstrong, and Munir Pirmohamed -- Pharmacogenomics of inflammatory bowel diseaes / Alexander Teml [and others] -- Pharmacogenetics of pain medication / J. Loetsch -- Ethical and social issues in pharmacogenomics testing / S. Vijverberg, T. Pieters, and M. Cornel -- High-throughput genotyping technologies for pharmacogenetics / Beatriz Sobrino and Dr. Angel Carracedo -- Developments in analyses in pharmacogenetic datasets / A. Motsinger -- Applications of pharmacogenetics in pharmaceutical research and development / Daniel K. Burns and Scott S. Sundseth -- Role of pharmacogenetics in registration process / Myong-Jin Kim [and others] -- Pharmacogenetics : possibilities and pitfalls / A.H. Maitland-van der Zee and A.K. Daly.
520 _a"Pharmacogenetics and Individualized Therapy offers thorough coverage of the study of the genetic determinants of drug response at the single gene level--and its impact on pharmaceuticals, therapeutics, and clinical practice. Providing an overview of the molecular basis of pharmacogenetics, the book helps readers understand the implications of genetic variability on pharmacokinetics and pharmacodynamics, as well as other aspects such as adverse drug reactions. Providing coverage of specific disease areas, including cardiovascular concerns, cancer and asthma/COPD, transplantation, and pain medication, the book also looks at the clinical practices, along with the psychiatric and ethical issues that have come to dominate conversation about pharmacogenetics."--
_cProvided by publisher.
588 0 _aPrint version record.
650 0 _aPharmacogenetics.
650 4 _aIndividualized Medicine
_xmethods.
650 4 _aPharmacy.
650 4 _aMedicine.
650 7 _aMEDICAL
_xDrug Guides.
_2bisacsh
650 7 _aMEDICAL
_xNursing
_xPharmacology.
_2bisacsh
650 7 _aMEDICAL
_xPharmacology.
_2bisacsh
650 7 _aMEDICAL
_xPharmacy.
_2bisacsh
650 7 _aPharmacogenetics.
_2fast
_0(OCoLC)fst01060243
650 2 _aPharmacogenetics
_xmethods.
650 2 _aDrug Therapy
_xmethods.
650 2 _aPrecision Medicine
_xmethods.
655 4 _aElectronic books.
655 7 _aElectronic books.
_2local
700 1 _aMaitland-van der Zee, Anke-Hilse.
700 1 _aDaly, Ann K.
776 0 8 _iPrint version:
_tPharmacogenetics and individualized therapy.
_dHoboken, N.J. : John Wiley & Sons, ©2011
_z9786613620330
_w(DLC) 2011015209
_w(OCoLC)712765625
856 4 0 _uhttp://onlinelibrary.wiley.com/book/10.1002/9781118116494
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