000 | 06835cam a2200913 i 4500 | ||
---|---|---|---|
001 | ocn836557859 | ||
003 | OCoLC | ||
005 | 20171224114249.0 | ||
006 | m o d | ||
007 | cr ||||||||||| | ||
008 | 130405s2013 nju ob 001 0 eng | ||
010 | _a 2013014142 | ||
040 |
_aDLC _beng _erda _epn _cDLC _dYDX _dN$T _dIDEBK _dEBLCP _dMHW _dCUS _dDG1 _dYDXCP _dCDX _dNOC _dCOO _dOCLCF _dE7B _dRECBK _dAU@ _dDEBSZ _dDEBBG _dOCLCQ |
||
019 |
_a853604182 _a864910982 _a889291911 _a927507960 _a961596246 _a962576425 |
||
020 |
_a9781118355879 _q(epub) |
||
020 |
_a1118355873 _q(epub) |
||
020 |
_a9781118355862 _q(pdf) |
||
020 |
_a1118355865 _q(pdf) |
||
020 |
_a9781118355855 _q(mobi) |
||
020 |
_a1118355857 _q(mobi) |
||
020 |
_a9781118355886 _q(electronic bk.) |
||
020 |
_a1118355881 _q(electronic bk.) |
||
020 |
_a0470572183 _q(cloth) |
||
020 |
_a9780470572184 _q(cloth) |
||
020 |
_a9781299665194 _q(MyiLibrary) |
||
020 |
_a1299665195 _q(MyiLibrary) |
||
020 |
_z9780470572184 _q(cloth) |
||
028 | 0 | 1 |
_aEB00063423 _bRecorded Books |
029 | 1 |
_aAU@ _b000050743027 |
|
029 | 1 |
_aAU@ _b000053306405 |
|
029 | 1 |
_aCHBIS _b010026978 |
|
029 | 1 |
_aCHVBK _b306244586 |
|
029 | 1 |
_aDEBBG _bBV041910078 |
|
029 | 1 |
_aDEBSZ _b431439060 |
|
029 | 1 |
_aDKDLA _b820120-katalog:000665215 |
|
029 | 1 |
_aNZ1 _b15340368 |
|
029 | 1 |
_aDEBBG _bBV043395717 |
|
035 |
_a(OCoLC)836557859 _z(OCoLC)853604182 _z(OCoLC)864910982 _z(OCoLC)889291911 _z(OCoLC)927507960 _z(OCoLC)961596246 _z(OCoLC)962576425 |
||
042 | _apcc | ||
050 | 0 | 0 | _aQD281.O9 |
072 | 7 |
_aSCI _x056000 _2bisacsh |
|
082 | 0 | 0 |
_a571.9/453 _223 |
049 | _aMAIN | ||
245 | 0 | 0 |
_aMolecular basis of oxidative stress : _bchemistry, mechanisms, and disease pathogenesis / _cedited by Frederick A. Villamena, Department of Pharmacology and Davis Heart and Lung Institute, the Ohio State University, Columbus, Ohio, USA. |
264 | 1 |
_aHoboken, New Jersey : _bWiley, _c[2013] |
|
300 | _a1 online resource. | ||
336 |
_atext _btxt _2rdacontent |
||
337 |
_acomputer _bc _2rdamedia |
||
338 |
_aonline resource _bcr _2rdacarrier |
||
504 | _aIncludes bibliographical references and index. | ||
588 | 0 | _aPrint version record and CIP data provided by publisher. | |
520 | _aFocusing on the molecular and chemical bases of oxidative stress, which can cause cancer as well as cardiovascular and neurodegenerative diseases, Molecular Basis of Oxidate Stress discusses the role of free radicals in disease, diagnosis, and therapeutics. Written by recognized leaders in the field, the book provides in-depth knowledge about the mechanisms of oxidative stress and damage, free radical chemistry, and the role of free radicals in disease, diagnosis, and therapeutics. | ||
505 | 0 | _a""Title page""; ""Copyright page""; ""Preface""; ""About the Contributors""; ""Contributors""; ""1: Chemistry of Reactive Species""; ""1.1 Redox Chemistry""; ""1.2 Classification of Reactive Species""; ""1.3 Reactivity""; ""1.4 Origins of Reactive Species""; ""1.5 Methods of Detection""; ""2: Lipid Peroxidation and Nitration""; ""Overview""; ""2.1 Peroxidation of PUFAs""; ""2.2 Cyclic Endoperoxides and Their Products""; ""2.3 Fragmented Products of Lipid Peroxidation""; ""2.4 Epoxy Fatty Acids""; ""2.5 Lipid Nitrosylation""; ""Summary""; ""3: Protein Posttranslational Modification"" | |
505 | 8 | _a""Overview""""3.1 Oxidative Stress-Related PTMs: Oxidation Reactions""; ""3.2 Amino Acid Modification by Oxidation-Produced Electrophiles""; ""3.3 Detection of Oxidative-Stress Related PTM""; ""3.4 Role of PTMs in Cellular Redox Signaling""; ""Summary""; ""4: DNA Oxidation""; ""Overview""; ""4.1 The Context of Cellular DNA Oxidation""; ""4.2 Oxidation of Oligonucleotides""; ""4.3 Examination of Specific Oxidative Lesions""; ""Future Outlook of DNA Oxidative Lesions""; ""5: Downregulation of Antioxidants and Phase 2 Proteins""; ""Overview"" | |
505 | 8 | _a""5.1 Definitions of Antioxidants and Phase 2 Proteins""""5.2 Roles in Oxidative Stress""; ""5.3 Molecular Regulation""; ""5.4 Induction in Chemoprevention""; ""5.5 Downregulation""; ""Conclusions and Perspectives""; ""6: Mitochondrial Dysfunction""; ""Overview""; ""6.1 Mitochondria and Submitochondrial Particles""; ""6.2 Energy Transduction""; ""6.3 Mitochondrial Stress""; ""6.4 Superoxide Radical Anion Generation as Mediated by ETC and Disease Pathogenesis""; ""Summary""; ""7: NADPH Oxidases: Structure and Function""; ""Overview""; ""7.1 Introduction"" | |
505 | 8 | _a""7.2 Phagocyte NADPH Oxidase Structure""""7.3 Phagocyte ROS Production""; ""7.4 Phagocyte NADPH Oxidase Function""; ""7.5 Nonphagocyte NADPH Oxidase Structure""; ""7.6 Nonphagocyte ROS Production""; ""7.7 Functions of Nonphagocyte NADPH Oxidases""; ""Summary""; ""Acknowledgments""; ""8: Cell Signaling and Transcription""; ""Overview""; ""8.1 Common Mechanisms of Redox Signaling""; ""8.2 Redox and Oxygen-Sensitive Transcription Factors in Prokaryotes""; ""8.3 Redox Signaling in Metazoans""; ""8.4 Oxygen Sensing in Metazoans""; ""8.5 Medical Significance of Redox and Oxygen-Sensing Pathways"" | |
505 | 8 | _a""Concluding Remarks""""9: Oxidative Stress and Redox Signaling in Carcinogenesis""; ""Overview""; ""9.1 Redox Environment and Cancer""; ""9.2 Oxidative Modifications to Biomolecules and Carcinogenesis""; ""9.3 Measurement of Oxidative DNA Damage in Human Cancer""; ""9.4 Epigenetic Involvement in Oxidative Stress-Induced Carcinogenesis""; ""9.5 Deregulation of Cell Death Pathways by Oxidative Stress in Cancer Progression""; ""Conclusions and Perspective""; ""Acknowledgments""; ""10: Neurodegeneration from Drugs and Aging-Derived Free Radicals""; ""Overview""; ""10.1 ROS Formation"" | |
650 | 0 | _aOxidative stress. | |
650 | 0 | _aOxidation. | |
650 | 4 | _aOxidative stress. | |
650 | 7 |
_aSCIENCE _xLife Sciences _xAnatomy & Physiology. _2bisacsh |
|
650 | 7 |
_aOxidation. _2fast _0(OCoLC)fst01049555 |
|
650 | 7 |
_aOxidative stress. _2fast _0(OCoLC)fst01049566 |
|
655 | 4 | _aElectronic books. | |
655 | 7 |
_aElectronic books. _2local |
|
700 | 1 | _aVillamena, Frederick A. | |
776 | 0 | 8 |
_iPrint version: _tMolecular basis of oxidative stress. _dHoboken, New Jersey : Wiley, [2013] _z9780470572184 _w(DLC) 2013002853 |
856 | 4 | 0 |
_uhttp://onlinelibrary.wiley.com/book/10.1002/9781118355886 _zWiley Online Library |
938 |
_aCoutts Information Services _bCOUT _n25731988 |
||
938 |
_aEBL - Ebook Library _bEBLB _nEBL1211621 |
||
938 |
_aebrary _bEBRY _nebr10718830 |
||
938 |
_aEBSCOhost _bEBSC _n593373 |
||
938 |
_aIngram Digital eBook Collection _bIDEB _ncis25731988 |
||
938 |
_aRecorded Books, LLC _bRECE _nrbeEB00063423 |
||
938 |
_aYBP Library Services _bYANK _n10753953 |
||
938 |
_aYBP Library Services _bYANK _n10350535 |
||
938 |
_aYBP Library Services _bYANK _n12672264 |
||
994 |
_a92 _bDG1 |
||
999 |
_c12656 _d12656 |