000			02756cam a2200373Ia 4500
001			CRC00E54376PDF
003			FlBoTFG
005			20171224123652.0
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007			cr||||
008			130702s2009 nyuadf sb 001 0 eng d
020			_a9781420054385 (ebook : PDF)
040			_aFlBoTFG _cFlBoTFG
090			_aRA1224.45 _b.D47 2009
092			_a618.32 _bD489
245	0	0	_aDevelopmental toxicology _h[electronic resource].
250			_a3rd ed. / _bedited by Deborah K. Hansen, Barbara D. Abbott.
260			_aNew York : _bInforma Healthcare, _cc2009.
300			_ax, 384 p., [8] p. of plates : _bill. (some col.).
490	1		_aTarget organ toxicology series ; _vv. 27
504			_aIncludes bibliographical references and index.
505	0		_a1. Role of apoptosis in normal and abnormal development / Philip Mirkes -- 2. Signal transduction pathways as targets for teratogens / Barbara D. Abbott -- 3. Nutrition in developmental toxicology / Deborah K. Hansen -- 4. Epigenetic mechanisms : role of DNA methylation, histone modifications, and imprinting / Robert G. Ellis-Hutchings and John M. Rogers -- 5. Personalized nutrition and medicine in perinatal development / Jim Kaput, James J. Chen, and William Slikker, Jr. -- 6. Targeted gene changes affecting developmental toxicity / Sid Hunter and Phillip Hartig -- 7. Use of mammalian in vitro systems, including embryonic stem cells, in developmental toxicity testing / Terence R.S. Ozolin�s -- 8. Zebrafish : a nonmammalian model of developmental toxicology / Kimberly C. Brannen ... [et al.] -- 9. Physiologically based pharmacokinetic modeling in the risk assessment of developmental toxicants / Mathieu Valcke and Kannan Krishnan -- 10. Integration of whole animal developmental toxicity data into risk assessment / Mark E. Hurtt and Gregg D. Cappon -- 11. Genomic approaches in developmental toxicology / George P. Daston and Jorge M. Naciff -- 12. Comparative bioinformatics and computational toxicology / Thomas B. Knudsen and Robert J. Kavlock -- 13. Investigating drug effects in human pregnancy / Christina D. Chambers
530			_aAlso available in print edition
538			_aMode of access: World Wide Web
650			_aDevelopmental toxicology
650			_aFetus _xEffect of drugs on
650			_aTeratogenic agents
655			_aElectronic books. _2lcs
700			_aHansen, Deborah Kay, _d1952
700			_aAbbott, Barbara D
776			_z9781420054378 (hardcover : alk. paper) _z1420054376 (hardcover : alk. paper
830			_aTarget organ toxicology series ; _vv. 27
856			_uhttp://marc.crcnetbase.com/isbn/9781420054385 _qapplication/PDF _zDistributed by publisher. Purchase or institutional license may be required for access
999			_c15486 _d15486