000			03065nam a2200373Ia 4500
001			CRC0KE10502PDF
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005			20171224123947.0
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007			cr||||
008			110413s2011 flua sb 001 0 eng d
020			_a9781439810729 (ebook : PDF)
040			_aFlBoTFG _cFlBoTFG
090			_aQP551 _b.K465 2011
092			_a572.6 _bK423
100	1		_aKessel, Amit.
245	1	0	_aIntroduction to proteins _h[electronic resource] : _bstructure, function, and motion / _cAmit Kessel and Nir Ben-Tal.
260			_aBoca Raton : _bCRC Press, _c2011.
300			_axxvii, 626 p. : _bill. (chiefly col.).
490	1		_aChapman & Hall/CRC mathematical and computational biology series
504			_aIncludes bibliographical references and index.
520			_a"The book aims to provide the reader with a detailed description of protein structure and dynamics, combined with an in-depth discussion of the relationship between both these aspects and protein function. Adopting the structural-biophysical approach, we discuss these in relation to molecular interactions and thermodynamic changes that transpire in this highly complex system. There are several types of textbooks describing protein structure and function. Biochemistry textbooks emphasize the functional aspect of proteins and provide a rather general description of structure and structure-function relationship (SFR). Structural Biology textbooks provide an extensive description of protein structure and also refer to SFR with varying degrees of detail. However, energy-related aspects are often avoided. Molecular biophysics textbooks focus on molecular interactions and thermodynamic aspects of protein structure, but tend to lack detailed description of structural and dynamic aspects, as well as SFR. Our book refers to all of the aforementioned aspects and attempts to provide a unified view. Our energy-oriented approach is manifested throughout the book, whether we discuss structure, dynamics or specific functions of proteins. An extensive discussion of the energetics of protein structure is also given in a chapter dedicated to this topic"--Provided by publisher.
505	0		_ach. 1. Introduction -- ch. 2. Protein structure -- ch. 3. Methods of structure determination and prediction -- ch. 4. Energetics and protein stability -- ch. 5. Protein structural dynamics -- ch. 6. Non-globular proteins -- ch. 7. Membrane proteins -- ch. 8. Protein-ligand interactions.
530			_aAlso available in print edition.
538			_aMode of access: World Wide Web.
650		0	_aProteins.
650		0	_aProteins _xStructure-activity relationships.
650		0	_aPhysical biochemistry.
655		7	_aElectronic books. _2lcsh
700	1		_aBen-Tal, Nir.
776	1		_z9781439810712
830		0	_aChapman & Hall/CRC mathematical and computational biology series (Unnumbered)
856	4	0	_uhttp://marc.crcnetbase.com/isbn/9781439810729 _qapplication/PDF _zDistributed by publisher. Purchase or institutional license may be required for access.
999			_c16102 _d16102